[1]杨 鹏,庞芳宁△,白 槟,等.胃癌淋巴结清扫数目与预后关系探讨*[J].陕西医学杂志,2020,49(8):987.[doi:DOI:10.3969/j.issn.1000-7377.2020.08.019]
　YANG Peng,PANG Fangning,BAI Bin,et al.The relationship between the number of lymph node removed and the prognosis of gastric cancer[J].,2020,49(8):987.[doi:DOI:10.3969/j.issn.1000-7377.2020.08.019]
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胃癌淋巴结清扫数目与预后关系探讨*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年8期
页码:
987
栏目:
临床研究
出版日期:
2020-08-05

文章信息/Info

Title:
The relationship between the number of lymph node removed and the prognosis of gastric cancer
作者:
杨 鹏1; 庞芳宁1△; 白 槟2; 赵青川2; 蒋金泉1
1.西安国际医学中心医院(西安 710100); 2.空军军医大学西京医院(西安 710032)
Author(s):
YANG Peng; PANG Fangning; BAI Bin; et al.
Xi'an International Medical Center Hospital(Xi'an 710100)
关键词:
胃癌;  淋巴结清扫数目;  肿瘤部位;  肿瘤大小;  TNM分期;  生存期
Keywords:
Gastric cancer;  Number of lymph node removed;  Tumor site;  Tumor size;  TNM staging;  Survival period
分类号:
R735.2
DOI:
DOI:10.3969/j.issn.1000-7377.2020.08.019
文献标志码:
A
摘要:
目的:探讨胃癌淋巴结清扫数目与预后的关系。方法:选取胃癌根治术清扫淋巴结数≥15枚的患者1443例,分为15～20枚、21～25枚、26～30枚、大于30枚四组。按照不同肿瘤部位、肿瘤大小、T分期、TNM分期,分别探讨淋巴结清扫数与生存期的相关性。结果:肿瘤≤5 cm并清扫26～30枚淋巴结组,胃体部肿瘤清扫21～25枚淋巴结组患者生存期均优于其余淋巴结组,组间比较差异有统计学意义(P<0.05)。结论:肿瘤≤5 cm清扫26～30枚淋巴结,胃体部肿瘤清扫21～25枚淋巴结组患者能延长生存期,清扫超过30枚淋巴结时,未见患者生存期明显增加。
Abstract:
Objective:To explore the relationship between the number of lymph node removed and the prognosis of gastric cancer.Methods:1443 gastric cancer patients with more than 15 lymph nodes removed were selected.They were divided into four groups:15-20,21-25,26-30 and more than 30.According to different tumor location,tumor size,T stage and TNM stage,the correlation between the number of lymph node removed and survival period was studied.Results:The survival time of the patients in the group of tumor ≤5 cm and 26-30 lymph nodes removed,and 21-25 lymph nodes removed in gastric body tumor was better than that in the other groups.Conclusion:The remove of 26-30 lymph nodes in the group with tumor≤5 cm and 21-25 lymph nodes in the group with gastric body tumor can prolong the survival period.When more than 30 lymph nodes are removed,there is no significant increase in the survival period of patients.

参考文献/References:

[1] Deng JY,Han L.Clinical significance of lymph node metastasis in gastric cancer[J].World J Gastroenterol,2014,20(14 ):3967-3975.
[2] Chen JH,Cai SR,Wu H,et al.Prognostic value of three different lymph node staging systems in the survival of patients with gastric cancer following D2 lymphadenectomy[J].Tumour Biol,2016,37(8):11105-11113.
[3] Chen W,Zheng R,Baade PD,et al.Cancer statistics in China,2015[J].CA Cancer J Clin,2016,66(2):115-132.
[4] 杨之洵,郑荣寿,张思维,等.中国胃癌发病趋势及预测[J].中国肿瘤,2019,28(5):321-326.
[5] 李彩雯,王玲玲,兰 琼,等.108例年轻胃癌患者临床病理特征分析[J].西安交通大学学报:医学版,2019,40(6):922-926.
[6] 郑潇豪,解亦斌.中国晚期胃癌的诊疗现状[J].癌症进展,2019,17(1):13-19.
[7] 宋 武,何裕隆.早期胃癌淋巴结转移特点、规律和意义[J].中国实用外科杂志,2019,39(5):444-447.
[8] 陈东方,王新妹.影响胃癌根治术术后生存期的多因素分析[J].中国现代医生,2018,56(13):91-93.
[9] 刘宏刚,薛英威.淋巴结转移度对胃癌患者术后生存期的评估价值[J].医学综述,2018,24(19):3923-3927.
[10] 钟广俊.无淋巴结转移胃癌患者预后分析[J].江苏医药,2018,44(7):791-793.
[11] 郑 涛,刘世呈.腹腔镜与传统开腹术联合淋巴结清扫治疗进展期老年胃癌的疗效、预后及安全性评估[J].实用癌症杂志,2019,34(2):267-270.
[12] 王 元,姜淮芜,徐 亮,等.胃裸区淋巴结清扫对胃癌患者预后的影响[J].中国现代医学杂志,2017,27(6):97-100.
[13] 魏晟宏,陈路川,叶再生,等.胃癌肿瘤大小的临床病理特征及预后分析(附753例报告)[J].福建医药杂志,2017,39(6):88-91.
[14] 陕 飞,李子禹,张连海,等.国际抗癌联盟及美国肿瘤联合会胃癌TNM分期系统(第8版)简介及解读[J].中国实用外科杂志,2017,37(1):15-17.
[15] Seshadri RA,Glehen O.Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in gastric cancer[J].World J Gastroenterol,2016,22(3):1114-1130.
[16] 王爱红,黄兰燕,米志宽.中药抑制胃癌肿瘤细胞增殖研究进展[J].陕西中医,2018,39(3):403-405.
[17] 常 青.胃癌根治术后影响预后的相关因素分析[J].陕西医学杂志,2017,46(8):1041-1042.

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备注/Memo

备注/Memo:
*国家重点研发计划项目子课题(2017YFC1311002,2017YFC1311004)
更新日期/Last Update: 2020-08-04