[1]彭茂轩,高彦斌,方海林△.间歇性充气加压装置联合利伐沙班应用于脊柱手术后血栓形成预防效果观察[J].陕西医学杂志,2020,49(5):568-570,574.
　PENG Maoxuan,GAO Yanbin,FANG Hailin..Preventive effect of intermittent pneumatic compression device combined with rivaroxaban on thrombosis after spinal surgery[J].,2020,49(5):568-570,574.
点击复制

间歇性充气加压装置联合利伐沙班应用于脊柱手术后血栓形成预防效果观察

《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年5期
页码:
568-570,574
栏目:
临床研究
出版日期:
2020-05-05

文章信息/Info

Title:
Preventive effect of intermittent pneumatic compression device combined with rivaroxaban on thrombosis after spinal surgery
文章编号:
DOI:10.3969/j.issn.10007377.2020.05.015
作者:
彭茂轩; 高彦斌; 方海林△
陕西省结核病防治院(陕西省第五人民医院)外科(西安710100)
Author(s):
PENG Maoxuan; GAO Yanbin; FANG Hailin.
Department of Surgery,Shaanxi Tuberculosis Prevention and Treatment Hospital(Fifth People's Hospital of Shaanxi Province)(Xi'an 710100)
关键词:
脊柱手术;  血栓;  预防;  间歇性充气加压装置;  利伐沙班;  凝血功能
Keywords:
Spinal surgery;  Thrombosis;  Prevention;  Intermittent pneumatic compression device;  Rivaroxaban;  Coagulation function
分类号:
R687.3
文献标志码:
A
摘要:
目的:探讨间歇性充气加压装置联合利伐沙班应用于脊柱手术血栓形成的预防效果。方法:选取行脊柱手术的患者73例作为研究对象,采用随机数字表法分为两组,对照组36例使用单用利伐沙班预防血栓栓塞,试验组37例采用间歇性充气加压装置联合利伐沙班预防血栓栓塞,观察两组血栓发生率及预后情况。结果:试验组术后血栓栓塞发生率明显低于对照组(P<0.05); 两组患者术前各项临床功能指标检测结果比较差异无统计学意义(P>0.05); 试验组术后凝血酶原时间(PT)、凝血酶时间(TT)和活化部分凝血活酶时间(APTT)均高于对照组(P<0.05); 术后出血性并发症发生率比较试验组低于对照组(P<0.05)。结论:脊柱手术患者应用间歇性充气加压装置联合利伐沙班预防血栓栓塞效果显著,还能有效改善患者凝血功能,降低出血性并发症发生率。
Abstract:
Objective:To investigate the preventive effect of intermittent pneumatic compression device combined with rivaroxaban on thrombosis after spinal surgery. Methods:A total of 73 patients who underwent spinal surgery were selected and divided into control group(36 cases)and experimental group(37 cases)by random number table method. The control group was treated with rivaroxaban alone to prevent thromboembolism. The experimental group was treated with intermittent pneumatic compression device combined with rivaroxaban to prevent thromboembolism. The incidence and prognosis of thromboembolism in the two groups were observed. Results:The incidence of postoperative thromboembolism in the experimental group was significantly lower than that in the control group(P<0.05). There was no significant difference in the results of preoperative clinical functional indexes between the two groups(P>0.05). The PT,TT and APTT of the experimental group were higher than those of the control group(P<0.05). The incidence of postoperative hemorrhagic complications in the experimental group was significantly lower than that in the control group(P<0.05). Conclusion:The application of intermittent pneumatic compression device combined with rivaroxaban in the prevention of thromboembolism is effective. It can also effectively improve the coagulation function of patients and reduce the occurrence of hemorrhagic complications.

参考文献/References:

[1] 艾 鹏,潘 浩,陈 魁,等.血栓弹力图预防脊柱外科患者围手术期并发症的价值[J].浙江临床医学,2019,21(1):1-3.
[2] Yilmaz B,Eksi MS,Toktas ZO,et al.Cerebral venous thr- ombosis following spinal surgery in a patient with factor V leiden mutation[J].British Journal of Neurosurgery,2016,30(4):456-458.
[3] 易伟林,梁 斌.脊柱手术后深静脉血栓形成的危险因素及预防的研究进展[J].医学综述,2016,22(23):4641-4645.
[4] 王东海,邢文华,祝 勇,等.成人脊柱术后下肢深静脉血栓形成的防治对策[J].实用骨科杂志,2017,23(5):416-421.
[5] 周益彪,张 斌.关注脊柱外科手术后的深静脉血栓:预防及治疗[J].中国组织工程研究,2017,21(27):4416-4422.
[6] 汪勇刚,王大鹏,徐林军.胸腰椎骨折术后口服利伐沙班预防深静脉血栓形成[J].临床骨科杂志,2017,20(3):304-306.
[7] 王东海,邢文华,祝 勇,等.脊柱术后早期分层预防静脉血栓栓塞症的疗效分析[J].脊柱外科杂志,2017,15(4):227-232.
[8] 米元元,陈 婷,周英凤,等.脊柱外科术后患者深静脉血栓预防及管理的最佳证据总结[J].中华护理杂志,2019,54(2):288-294.
[9] Ryan M,Jonathan R,Brian RS,et al.Venous thromboembolism:a comparison of chronic spinal cord injury and general surgery patients in a metropolitan veterans affairs hospital[J].Plastic and Reconstructive Surgery,2016,138(5):908e-914e.
[10] 周云灿,余可谊,施举红,等.脊柱术后发生下肢深静脉血栓及多发肺栓塞1例报道并文献复习[J].中华骨与关节外科杂志,2018,11(12):940-943.
[11] 侯训凯,林永杰,石恩东,等.低分子肝素与利伐沙班预防脊柱外科手术后下肢深静脉血栓的疗效和安全性比较[J].中国药房,2015,(30):4221-4223.
[12] 叶 一,蒋国强,卢 斌,等.基于Caprini风险评估模型的腰椎椎管减压内固定术术后静脉血栓分级预防[J].脊柱外科杂志,2018,16(3):148-151.
[13] Koji Y,Masahiro H,Keita O,et al.Prevalence and risk factors of deep vein thrombosis in patients undergoing lumbar spine surgery[J].Journal of Orthopaedic Science,2017,22(6):1021-1025.
[14] 徐 晔,邱惠琴,秦 霞,等.抗血栓压力带在预防颅脑损伤术后患者下肢深静脉血栓形成中的应用[J].实用临床医药杂志,2017(18):118-119.
[15] 徐建杰,武建忠,董志辉,等.低分子肝素、间歇性充气加压装置预防脊柱手术后静脉栓塞症的疗效比较[J].现代中西医结合杂志,2016,25(7):738-739,767.
[16] 郑琪娈,沈 琪,余金聪,等.利伐沙班与血塞通注射液联合使用抑制脊柱术后下肢深静脉血栓形成的效果及血液指标的影响[J].中国临床药理学与治疗学,2018,23(3):337-341.
[17] 安 宁.高龄脊柱骨折患者围手术期下肢深静脉血栓形成的预防及护理[J].浙江临床医学,2016,18(10):1937-1938.

相似文献/References:

[1]童惠平,李 绒.心电图和超声心动图联合检查在非瓣膜性房颤患者左房室血栓诊断中的临床价值[J].陕西医学杂志,2021,50(7):811.[doi:DOI:10.3969/j.issn.1000-7377.2021.07.010]
　TONG Huiping,LI Rong.Clinical value of ECG combined with echocardiography in diagnosis of left atrial thrombus in patients with NVAF[J].,2021,50(5):811.[doi:DOI:10.3969/j.issn.1000-7377.2021.07.010]
[2]闫琼琼,王小玲.子痫前期孕产妇并发深静脉血栓危险评估及影响因素分析[J].陕西医学杂志,2021,50(10):1231.[doi:DOI:10.3969/j.issn.1000-7377.2021.10.013]
　YAN Qiongqiong,WANG Xiaoling.Risk assessment and influencing factors of deep vein thrombosis in pregnant women with preeclampsia[J].,2021,50(5):1231.[doi:DOI:10.3969/j.issn.1000-7377.2021.10.013]

更新日期/Last Update: 2020-07-28