[1]韩晓强,王化齐△.下肢创伤骨折患者健侧肢体深静脉血栓发生特点及危险因素分析[J].陕西医学杂志,2020,49(4):458-461,469.
 HAN Xiaoqiang,WANG Huaqi..Characteristics and risk factors of deep vein thrombosis in the contralateral limb of patients with traumatic fracture of lower extremity[J].,2020,49(4):458-461,469.
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下肢创伤骨折患者健侧肢体深静脉血栓发生特点及危险因素分析
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年4期
页码:
458-461,469
栏目:
临床研究
出版日期:
2020-04-05

文章信息/Info

Title:
Characteristics and risk factors of deep vein thrombosis in the contralateral limb of patients with traumatic fracture of lower extremity
文章编号:
DOI:10.3969/j.issn.10007377.2020.04.018
作者:
韩晓强王化齐
陕西省安康市中医医院骨科(安康725000)
Author(s):
HAN XiaoqiangWANG Huaqi.
Department of Orthopedics,Ankang Hospital of Traditional Chinese Medicine(Ankang 725000)
关键词:
创伤骨科 下肢骨折 深静脉血栓 健侧肢体 临床特点 危险因素
Keywords:
Traumatology and orthopedics Lower limb fracture Deep vein thrombosis Uninvolved limb Clinical characteristics Risk factor
分类号:
R658.3
文献标志码:
A
摘要:
目的:探究下肢创伤骨折患者健侧肢体深静脉血栓(DVT)发生特点及其危险因素。方法:回顾性分析511例接受手术治疗的下肢创伤性骨折患者临床资料。统计分析患者年龄、性别、体重指数(BMI)、骨折部位、合并症、创伤至手术时间、手术至出院时间、ASA分级、补液量、D-二聚体(D-D)水平、DVT发生时间、位置及首发症状等资料。分析影响健侧DVT发生的危险因素。结果:511例患者健侧DVT发生率为4.89%,主要发生于创伤3 d后(24.00%)和术后3 d(48.00%)内,以远端血栓为主(80.00%),疼痛或伴发热和肿胀发硬为其首发临床症状。患者年龄、骨折部位、创伤至手术时间、术后1 d D-D水平均是影响健侧下肢DVT形成的独立危险因素(P<0.05)。结论:下肢创伤骨折患者住院期间健侧肢体具有较高DVT发生风险,疼痛或伴发热和肿胀发硬为其首发临床症状,年龄、骨折部位、创伤至手术时间、术后1 d D-D水平均是影响健侧下肢DVT形成的独立危险因素,临床需加强对该类患者的围术期管理,预防DVT发生。
Abstract:
Objective:To investigate the characteristics and risk factors of deep vein thrombosis(DVT)in the contralateral limbs of patients with traumatic fracture of lower extremity. Methods:The clinical data of 511 patients with traumatic fracture of lower extremity who underwent surgical treatment were retrospectively analyzed. The age,gender,body mass index(BMI),fracture site,comorbidities,time from trauma to surgery,time from surgery to discharge,ASA classification,fluid infusion volume,D-dimer(DD)level,DVT occurrence time,location and first symptom,and other data were collected and analyzed. The risk factors influencing the occurrence of contralateral DVT were analyzed. Results:The incidence of DVT in the uninjured side of 511 patients was 4.89%,which mainly occurred within 3 days(24.00%)after trauma and 3 days after surgery(48.00%),with distal thrombus as the main symptom(80.00%),pain or accompanied by fever and swelling and stiffness as the first clinical symptom. The age,fracture site,time from trauma to surgery and 1 d D-D level after surgery were independent risk factors of DVT formation in the healthy side(P<0.05). Conclusion:Patients with lower extremity trauma fractures have higher risk of DVT during hospitalization. Pain or associated fever and swelling and stiffness are the first clinical symptoms. The age,fracture site,time from trauma to surgery and 1 d D-D level after surgery are independent risk factors affecting the formation of DVT in the healthy side of the lower extremity. Therefore,it is necessary to strengthen the perioperative management of such patients to prevent DVT.

参考文献/References:

[1] 王 轶,戚 颖. 疏血通联合低分子肝素治疗创伤后深静脉血栓疗效及对患者凝血功能和血流动力学水平影响[J]. 陕西中医,2019,40(1):69-71.
[2] 王晓燕,王 秀. 围生期孕产妇下肢深静脉血栓的临床特征、预后及影响因素分析[J]. 中国计划生育和妇产科,2016,8(9):28-31.
[3] 李辰阳,李鸿斌,罗雪峰,等. 下肢骨折术后深静脉血栓形成相关危险因素分析[J]. 新疆医科大学学报,2017,40(7):876-879.
[4] 李树灏,张 堃,衡立松,等. 下肢闭合骨折24小时内下肢深静脉血栓发生率及危险因素[J]. 国际骨科学杂志,2019,40(5):306-310.
[5] Decker S,Weaver MJ. Deep venous thrombosis following different isolated lower extremity fractures:what is known about prevalences,locations,risk factors and prophylaxis[J]?European Journal of Trauma & Emergency Surgery Official Publication of the European Trauma Society,2013,39(6):591-598.
[6] 王 军. 利伐沙班联合疏血通注射液预防下肢骨折术后深静脉血栓形成疗效及对患者血液流变学的影响[J]. 陕西医学杂志,2015,44(11):1530-1532.
[7] 朱晓玲,冯娜娜,王 明. 下肢深静脉血栓位置与下肢骨折部位的关系[J]. 实用骨科杂志,2018,24(1):84-85.
[8] 李嘉浩,张斌飞,王鹏飞,等. 下肢骨折患者健侧肢体深静脉血栓形成的发生率及危险因素分析[J]. 中华创伤骨科杂志,2018,20(12):1060-1065.
[9] 费 晨,魏 巍,张斌飞,等. 胫骨平台骨折患者围手术期下肢深静脉血栓形成发生规律及危险因素分析[J]. 中华创伤骨科杂志,2019,21(2):102-108.
[10] 张 营,汪颖厚,曹 宇,等. 不同年龄、季节对下肢深静脉血栓形成发病影响研究[J]. 临床军医杂志,2018,46(11):1385.
[11] 郭 慧,陈 锋,熊吉信,等. 不同患肢和年龄的继发性下肢深静脉血栓患者诱发因素分析[J]. 中国全科医学,2017,20(2):219-223.
[12] 中华医学会骨科学分会. 中国骨科大手术静脉血栓栓塞症预防指南[J]. 中华骨科杂志,2016,36(2):265.
[13] 臧加成,马信龙,马剑雄,等. 不同部位骨折深静脉血栓发生率的流行病学研究[J]. 中华骨科杂志,2016,36(9):540-545.
[14] 唐 颖,郭庆山,赵玉峰,等. 创伤骨折并发下肢深静脉血栓的危险因素分析[J]. 中华创伤杂志,2011,26(12):1122-1125.
[15] 范吉星,李 宁,龚晓峰,等. 老年髋部骨折术前下肢深静脉血栓形成的影响因素研究[J]. 中国矫形外科杂志,2017,25(22):2027-2031.
[16] 侍冬成,吴 蔚,赵 钢,等. D-二聚体峰值变化与下肢骨折、骨盆骨折患者深静脉血栓的关系研究[J]. 重庆医学,2011,40(13):1291-1293.

更新日期/Last Update: 2020-04-13