[1]邵亚军,雷霆宇,邵林海△.直肠B超会阴前列腺12点穿刺术对前列腺特异性抗原水平为4~10 ng/ml患者前列腺癌诊断价值[J].陕西医学杂志,2020,49(4):450-452,封3.
 SHAO Yajun,LEI Tingyu,SHAO Linhai..Diagnostic value of transrectal B-ultrasound-guided transperineal 12-core prostate puncture for prostate cancer patients with PSA 4~10 ng/ml[J].,2020,49(4):450-452,封3.
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直肠B超会阴前列腺12点穿刺术对前列腺特异性抗原水平为4~10 ng/ml患者前列腺癌诊断价值
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
49
期数:
2020年4期
页码:
450-452,封3
栏目:
临床研究
出版日期:
2020-04-05

文章信息/Info

Title:
Diagnostic value of transrectal B-ultrasound-guided transperineal 12-core prostate puncture for prostate cancer patients with PSA 4~10 ng/ml
文章编号:
DOI:10.3969/j.issn.10007377.2020.04.016
作者:
邵亚军1雷霆宇1邵林海2△
1.西安市第一医院超声科(西安 710002); 2.陕西省汉中市中心医院泌尿科(汉中 723000)
Author(s):
SHAO YajunLEI TingyuSHAO Linhai.
Department of Ultrasound,Xi'an NO.1 Hospital(Xi'an 710002)
关键词:
直肠B超 会阴前列腺 12点穿刺术 前列腺特异性抗原 前列腺癌
Keywords:
Rectal B-ultrasound Perineal prostate 12-core puncture Prostate specific antigen Prostate cancer
分类号:
R737.25
文献标志码:
A
摘要:
目的:探讨直肠B超会阴前列腺12点穿刺术对前列腺特异性抗原(PSA)4~10 ng/ml前列腺癌(PC)患者的诊断价值。方法:纳入经临床检查后疑似PC患者130例,根据穿刺方法的不同,分为会阴组(60例)和直肠组(70例)。会阴组行直肠B超会阴前列腺12点穿刺术,直肠组行B超下直肠前列腺12点穿刺术。对两组穿刺活检后的病理结果进行分析,对两组PC阳性患者疾病严重程度分布进行比较,比较会阴组和直肠组穿刺后不良反应发生率。结果:会阴组PC阳性率与直肠组比较无统计学差异(P>0.05)。会阴组共检出PC阳性患者29例(48.33%),直肠组共检出PC阳性患者21例(30.00%)。两组PC严重程度分布比较,差异有统计学意义(P<0.05)。会阴组感染、血便的发生率均明显低于直肠组(P<0.05)。会阴组和直肠组血尿和尿潴留发生率比较,差异无统计学意义(P>0.05)。会阴组的不良反应发生率明显低于直肠组(P<0.05)。结论:与经直肠途径相比,直肠B超下经会阴前列腺12点穿刺术的穿刺阳性率较高,安全性好,在PSA 4~10 ng/ml的患者中诊断价值更高。
Abstract:
Objective:To investigate the diagnostic value of transrectal B-ultrasound-guided transperineal 12-core prostate puncture for prostate cancer(PC)patients with PSA 4~10 ng/ml. Methods:130 suspected PC patients after clinical examination were enrolled and divided into perineum group(60 cases)and rectum group(70 cases)according to different puncture methods. The perineum group underwent transperineal 12-core prostate puncture,and the rectum group underwent transrectal 12-core prostate puncture. The pathological results of the two groups were analyzed. The distribution of disease severity in two groups of PC-positive patients,as well as the incidence of adverse reactions in two groups,were compared. The incidence of adverse reactions after puncture was compared between the perineal group and the rectal group. Results:The PC-positive rate in the perineal group was significantly higher than that in the rectal group(P>0.05). A total of 29 PC-positive patients(48.33%)were detected in the perineal group,and 21 PC-positive patients(30.00%)were detected in the rectal group. The distribution difference of PC severity between the two groups was statistically significant(P<0.05). The incidence of infection and bloody stool in the perineal group were significantly lower than those between the rectal group(P<0.05). There was no significant difference in the incidence of hematuria and urinary retention between the perineal group and rectal group(P>0.05). The incidence of adverse reactions in the perineal group was significantly lower than that in the rectal group(P<0.05). Conclusion:Compared with the transrectal approach,the percutaneous transrectal perineal prostate puncture under the B-mode ultrasound has a higher positive rate and better safety,which has higher diagnostic value in patients with PSA 4~10 ng/ml.

参考文献/References:

[1] Moon HC,Young JL,Seung EJ. the role of transrectal ultrasound for finding focal lesions in prostate cancer detection compared to systematic sextant biopsy[J]. Academic Radiology,2019,26(8):65-69.
[2] Perez-Ibave DC,Burciaga F,Carlos H,et al. Prostate-specific antigen(PSA)as a possible biomarker in non-prostatic cancer:A review[J]. Cancer Epidemiology,2018,54(6):48-55.
[3] 郑雨潇,张 成,吴 杰,等. 经直肠超声引导前列腺12+1针穿刺活检的临床研究[J]. 中华泌尿外科杂志,2017,38(5):375-378.
[4] 杜丽娜,康 峰,苏燕胜,等.围术期常规干预联合下腹部局部热敷在前列腺癌电切术后排尿困难患者中的应用研究[J].陕西医学杂志,2019,48(6):784-786,812.
[5] 钟 华,郭燕丽,张 丰,等.经直肠超声引导下前列腺穿刺活检结合血清PSA在诊断前列腺癌中的价值[J].第三军医大学学报,2016,38(6):638-641.
[6] 南新记,张至慧,周冬冬.鸦胆子油注射液对激素抵抗性前列腺癌VEGF-C及患者血清PSA水平的影响研究[J].陕西中医,2019,40(4):490-492.
[7] 王 磊,蒋淑婉,杨家佳,等. 直肠超声引导经会阴途径穿刺活检诊断前列腺癌[J]. 现代肿瘤医学,2017,25(18):89-95.
[8] Guo G,Xu Y,Zhang X. TRUS-guided transperineal prostate 12+X core biopsy with template for the diagnosis of prostate cancer[J]. Oncology Letters,2017,13(6):4863-4865.
[9] 王 尧,游向东,刘春媚,等. 超声造影引导靶向穿刺活检诊断老年前列腺特异性抗原灰区前列腺癌的价值[J]. 中国老年学杂志,2017,37(9):2191-2193.
[10] 朱 鹤,果宏峰,李宁忱,等. 徒手TRUS引导下经会阴前列腺活检的临床应用探讨[J]. 临床泌尿外科杂志,2018,33(2):156-159.
[11] 陈勇辉,张丽英,邹冰子. 经直肠超声引导下前列腺6点穿刺活检术诊断单纯前列腺特异抗原增高型前列腺癌[J]. 中国介入影像与治疗学,2015,12(6):332-335.
[12] 覃 斌,梁阳冰,梁毅文,等. 直肠超声引导下经会阴和直肠前列腺穿刺活检术诊断灰区前列腺癌的对比研究[J]. 中华男科学杂志,2016,22(5):477-479.
[13] 朱云海,孟 军,邹 政. 直肠超声引导下经会阴前列腺穿刺诊断前列腺癌的临床价值及并发症分析[J]. 中国中西医结合影像学杂志,2015,13(6):611-612.
[14] 周金才,倪 颖,王启明,等. 直肠B超引导下经会阴前列腺穿刺的50例体会[J]. 中华肿瘤防治杂志,2018,25(S1):152-153.
[15] 王晓岩,许新征,刘洋洋,等. 经直肠超声引导下前列腺穿刺活检术的临床运用分析[J]. 中国地方病防治杂志,2017,32(3):314.

更新日期/Last Update: 2020-04-13