[1]史阿娉,史成兴,杨志军,等.超声造影与彩色多普勒超声检查诊断卵巢肿瘤对比研究*[J].陕西医学杂志,2019,(5):628-631.
　SHI Aping,SHI Chengxing,YANG Zhijun,et al.Comparative analysis of contrastenhanced ultrasound and color doppler ultrasound in the identification of ovarian tumors[J].,2019,(5):628-631.
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超声造影与彩色多普勒超声检查诊断卵巢肿瘤对比研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年5期
页码:
628-631
栏目:
临床研究
出版日期:
2019-05-05

文章信息/Info

Title:
Comparative analysis of contrastenhanced ultrasound and color doppler ultrasound in the identification of ovarian tumors
文章编号:
DOI: 10.3969/j.issn.10007377.2019.05.024
作者:
史阿娉1; 史成兴1; 杨志军1; 关 卓1; 曹 馨2; 王文戈
1.西电集团医院超声科（西安 710077）;2.西电集团医院妇产科（西安 710077）
Author(s):
SHI Aping; SHI Chengxing; YANG Zhijun; et al.
Ultrasonography Department of Xi’an XD Group Hospital（Xi’an 710077）
关键词:
卵巢肿瘤; 良恶性; 诊断; 彩色多普勒超声; 造影; 影像特点
Keywords:
Key words Ovarian neoplasms; Benign and malignant; Diagnosis; Color doppler ultrasound; Angiography; 〖LM〗Image characteristics
分类号:
R445.1
文献标志码:
A
摘要:
摘 要 目的：探讨超声造影与常规彩色多普勒超声检查在卵巢肿瘤良恶性鉴别诊断中的应用价值。方法：回顾性分析76例经病理学诊断确诊良恶性的卵巢肿瘤患者的常规彩色多普勒超声及超声造影检查资料。分析两种检查方式在鉴别卵巢肿瘤良恶性方面的准确率及影像学特点。结果：76例卵巢肿瘤患者在超声造影检查中良、恶性结果与术后病理学符合率显著高于经常规彩色多普勒超声检查（90.24%与65.85%，88.57%与48.57%）（P＜0.05）。常规彩色多普勒超声检查显示，良性卵巢肿瘤血流特点以Ⅰ型为主，恶性以Ⅲ型为主，且良性肿瘤Finkler评分显著低于恶性肿瘤，RI值显著高于恶性肿瘤（P＜0.01）；超声造影检查显示：良性卵巢肿瘤灌注水平以低增强为主，恶性则以高增强为主，良性卵巢肿瘤灌注低增强例数显著多于恶性肿瘤，高增强例数显著少数恶性肿瘤（P＜0.01）；恶性卵巢肿瘤造影剂的Imax显著强于良性肿瘤，TTP、mTT显著短于良性肿瘤（P＜0.05）；而两者RT间差异无统计学意义（P＞0.05）。结论：与常规彩色多普勒超声检查相比，超声造影可更好的显示良恶性卵巢肿瘤组织及血管分布、灌注特点，且后续图像处理结果可进一步提高良恶性鉴别诊断的准确性。
Abstract:
Abstract Objective:To explore the value of contrastenhanced ultrasound and color Doppler ultrasonography in the differential diagnosis of benign and malignant ovarian tumors.Methods:The color doppler ultrasonography and contrastenhanced ultrasonography imaging data of 76 cases were confirmed the benign tumor or malignant tumor by pathological examination was analyzed retrospectively.The accuracy and imaging characteristics of the two methods of examination in identifying the benign and malignant ovarian tumors were analyzed.Results:The benign and malignant coincidence rate of contrastenhanced ultrasonography and postoperative pathology in 76 patients with ovarian tumors was significantly higher than that of color Doppler ultrasonography (90.24% vs 65.85%, 88.57% vs 48.57%) (P＜0.05).Color doppler ultrasonography showed that the blood flow characteristics of benign ovarian tumors were mainly type I, malignant type III was dominant, and the Finkler score of benign tumors was significantly lower than that of malignant tumors, and the RI value was significantly higher than that of malignant tumors (P＜0.01). Contrastenhanced ultrasonography showed that the perfusion level of benign ovarian tumors was mainly in low enhancement, while malignant was mainly high in enhancement;the number of benign ovarian tumor perfusion was significantly higher than that of malignant tumors, and the number of high enhancement patients was significantly different (P＜0.01),the Imax of contrast agents in malignant ovarian tumors was significantly stronger than that in benign tumors. TTP and mTT were significantly shorter than benign tumors (P＜0.05),there was no significant difference between the two groups (P＞0.05).Conclusion:Compared with conventional color Doppler ultrasonography, contrastenhanced ultrasound can better display the tissue and vascular distribution and perfusion characteristics of benign and malignant ovarian tumors, and the results of subsequent image processing can further improve the differential diagnosis of benign and malignant diagnosis.

参考文献/References:

[1] 杨五彪,马灵筠,万学东,等.血清CA125、CEA、AFP联合检测在卵巢肿瘤诊断中的价值[J].陕西医学杂志,2004,33(5):426-428. [2] Janicke F, Holscher M, Kuhn W, et al. Radical surgical procedure improves survival time in patients with recurrent ovarian cancer[J]. Cancer, 2015, 70(8):2129-2136. [3] Minlikeeva AN, Freudenheim JL, Eng KH, et al. History of comorbidities and survival of ovarian cancer patients,results from the ovarian cancer association consortium[J].Cancer Epidemiol Biomarkers Prev,2017, 26(9)：1470-1473. [4] 胡 娟, 徐 毅, 胡永胜, 等. 彩色多普勒超声对乳腺癌的诊断价值超声图形特征分析[J]. 陕西医学杂志,2014,43(9)：11921193. [5] 廖建梅, 杨舒萍, 陈顺姬, 等. 彩色多普勒超声引导下活检结合造影在卵巢肿瘤诊断中的应用[J]. 辽宁医学院学报, 2014, 13(5):389-392. [6] 王娟娟, 于 冰. 卵巢肿瘤彩超血流指标与微血管密度及促血管生成素的相关性[J]. 中国临床医学影像杂志,2015,26(10):728-731. [7] 王海霞, 刘景萍, 梁永平, 等. 肝细胞肝癌超声造影峰值强度与血管生成相关性分析[J]. 陕西医学杂志,2016,45(10):1307-1309. [8] 苗艳梅, 吕 伟, 张 宏,等. 经阴道彩色多普勒超声诊断卵巢早衰的临床价值[J]. 中国地方病防治杂志,2017,32(3)：344-344. [9] 胡 鸣, 洪 莉, 陈 璐, 等. 超声造影结合参数图像处理在诊断卵巢恶性肿瘤中的应用价值[J]. 临床超声医学杂志,2014,16(12):800-802. [10] 熊 希. 常规超声与超声造影诊断盆腔结核对比分析[J]. 中国介入影像与治疗学, 2015, 12(6):341-344. [11] 万小平, 苏应宽. 彩色多普勒超声对卵巢肿瘤内血管的定量分析[J]. 中华医学杂志, 2000, 80(9):672-674. [12] 李载红, 景香香, 游 佳, 等.超声造影在良恶性卵巢肿瘤鉴别诊断中的价值[J]. 中国医药导报, 2016, 13(1):117-120. [13] 李载红, 景香香. 超声造影在卵巢肿瘤临床检测中的应用[J]. 中国临床医学影像杂志, 2016, 27(1):62-65. [14] 秦伟芳, 刘 慧, 向 红, 等. 靶向与非靶向超声造影对卵巢癌血管生成拟态的对比研究[J]. 中国超声医学杂志, 2017, 33(12)：1123-1126.

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备注/Memo

备注/Memo:
*陕西省科学技术研究发展计划项目（2012R12487）
更新日期/Last Update: 2019-05-07