[1]刘国庆,闫 龙△,高 任.1.5T磁共振扩散加权成像在胃癌淋巴结转移诊断中的应用价值*[J].陕西医学杂志,2019,(4):456-458,462.
　LIU Guoqing,YAN Long,GAO Ren..1.5T magnetic resonance diffusion weighted imaging in the diagnosis of lymph node metastasis of gastric cancer[J].,2019,(4):456-458,462.
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1.5T磁共振扩散加权成像在胃癌淋巴结转移诊断中的应用价值*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年4期
页码:
456-458,462
栏目:
临床研究
出版日期:
2019-04-05

文章信息/Info

Title:
1.5T magnetic resonance diffusion weighted imaging in the diagnosis of lymph node metastasis of gastric cancer
文章编号:
DOI: 10.3969/j.issn.10007377.2019.04.013
作者:
刘国庆1; 闫 龙2△; 高 任
1.陕西省中医医院影像中心 （西安 710003）；2.陕西省延安市人民医院CT室（ 延安 716000）
Author(s):
LIU Guoqing;  YAN Long;  GAO Ren.
Image Center, Shaanxi Provincial Hospital of Traditional Chinese Medicine（Xi'an 710003）
关键词:
磁共振; 扩散加权成像; 胃癌; 淋巴结转移; 特征曲线; 诊断
Keywords:
Key words Magnetic resonance;  Diffusionweighted imaging;  Gastric cancer;  Lymph node metastasis; Receiver operating characteristic curve; Diagnosis〖HJ1〗
分类号:
R735.2
文献标志码:
A
摘要:
摘 要 目的：探讨1.5T磁共振扩散加权成像（DWI）在胃癌淋巴结转移诊断中的应用价值。方法：选择行1.5T磁共振腹部检查的95例胃癌患者，所有患者均给予常规序列及DWI序列扫描，以术后病理或临床随访为“金标准”，观察转移淋巴结与非转移淋巴结MR表现，并绘制受试者工作特征曲线（ROC）比较淋巴结长径、短径及ADC值诊断效能。结果：①95例患者共检出肿大淋巴结146枚，转移性与非转移性淋巴结分别为81枚、65枚。在MR信号是否均匀及是否成簇分布方面，转移性淋巴结与非转移性淋巴结比较，差异均无统计学意义（P>0.05）；②转移淋巴结长径、短径均大于非转移淋巴结，但差异无统计学意义（P>0.05），转移淋巴结ADC值小于非转移淋巴结，差异有统计学意义（P<0.05）；③ROC曲线分析：长径、短径、ADC值曲线下面积分别为0.514、0.505、0.866，阈值分别为1.915 mm、1.200 mm、0.750×103mm2/s；ADC值敏感度、特异度分别为82.9%、71.1%，显著高于长径（56.1%、47.4%）及短径（61.0%、53.3%）。结论：1.5T磁共振DWI序列在胃癌淋巴结转移诊断中具有较高敏感度及特异度。
Abstract:
Abstract Objective:To investigate the value of 1.5T magnetic resonance diffusion weighted imaging (DWI) in the diagnosis of lymph node metastasis of gastric cancer. Methods ：95 patients with gastric cancer who underwent 1.5T magnetic resonance abdomen examination were studied, all patients were given routine sequence and DWI sequence scans. Followup pathological or clinical followup for the "gold standard" to observe the metastatic lymph nodes and nonmetastatic lymph node MR performance, and draw the receiver operating characteristic curve (ROC) curve to compare lymph node long diameter, short diameter and ADC diagnostic efficiency. Results ：A total of 146 enlarged lymph nodes were detected in 95 patients, 81 metastatic and 65 nonmetastatic lymph nodes. In terms of MR signal uniformity and distribution, there was no significant difference between metastatic lymph nodes and nonmetastatic lymph nodes (P>0.05). The long and short diameters of the metastatic lymph nodes were larger than those of the nonmetastatic lymph nodes, but the difference was not statistically significant (P>0.05). The ADC value of the metastatic lymph nodes was smaller than that of the nonmetastatic lymph nodes (P<0.05). ROC curve analysis: the area under the long diameter, short diameter, and ADC values were 0.514, 0.505, and 0.866, and the thresholds were 1.915 mm and 1.200 mm, and 0.750×103mm2/s; the sensitivity and specificity of ADC were 82.9%, 71.1%, significantly higher than long diameter (56.1%, 47.4%) and short diameter (61.0%, 53.3%). Conclusion： 1.5T magnetic resonance DWI sequence has high sensitivity and specificity in the diagnosis of lymph node metastasis of gastric cancer.

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备注/Memo

备注/Memo:
*陕西省科技计划项目（2017SF128）
更新日期/Last Update: 2019-04-10