[1]李泽平,陈彦霖,李晓苗,等.Mash1基因对神经干细胞分化与神经发育的影响研究进展[J].陕西医学杂志,2019,(3):404-406.
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Mash1基因对神经干细胞分化与神经发育的影响研究进展
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年3期
页码:
404-406
栏目:
综述
出版日期:
2019-03-05

文章信息/Info

文章编号:
DOI:10.3969/j.issn.10007377.2019.03.033
作者:
李泽平1;  陈彦霖1; 李晓苗2; 焦慧凤
1.南昌大学玛丽女王学院（南昌330031）；2.空军军医大学西京医院（西安 710032），3.南昌大学生命科学院（南昌330031)
关键词:
bHLH; Mash1; 神经干细胞; 神经发育
分类号:
R338
文献标志码:
A
摘要:
摘 要 Mash1基因属于碱性螺旋环螺旋基因(basic helixloophelex，bHLH)家族，其存在对于神经发育有重大影响作用，其作用机制同Hes基因及Notch通路有复杂而紧密的联系。Hes基因可以拮抗Mash1基因表达，Notch通路可通过不同方式起调控二者作用。Mash1对于神经干细胞分化和决定细胞命运以及神经发育具有重大作用。

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更新日期/Last Update: 2019-03-15