[1]曹 馨.腹腔镜子宫切除术对患者机体免疫功能的影响研究[J].陕西医学杂志,2019,(3):345-347,351.
　CAO Xin..Effects of laparoscopic hysterectomy on immune functionof the body[J].,2019,(3):345-347,351.
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腹腔镜子宫切除术对患者机体免疫功能的影响研究
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年3期
页码:
345-347,351
栏目:
基础研究
出版日期:
2019-03-05

文章信息/Info

Title:
Effects of laparoscopic hysterectomy on immune functionof the body
文章编号:
DOI:10.3969/j.issn.10007377.2019.03.016
作者:
曹 馨
西电集团医院妇产科(西安 710077）
Author(s):
CAO Xin.
Xidian Group Hospital（Xi’an 710077)
关键词:
腹腔镜子宫切除术; 开腹子宫切除术; 免疫球蛋白; 免疫球蛋白M; 免疫球蛋白A; C反应蛋白
Keywords:
Key words Laparoscopic; Hysterectomy; Laparohysterectomy; Immunoglobulin G; Immunoglobulin M; Immunoglobulin A; Creactive protein
分类号:
R713.4
文献标志码:
A
摘要:
摘 要 目的：研究腹腔镜子宫（LH）和开腹子宫切除术（AH）对机体免疫功能的影响。方法：检测腹腔镜子宫（LH）30例和开腹子宫切除术（AH）30例患者术前24 h、术后48h的血清免疫球蛋白IgG、IgA、IgM，补体 C3、C4和 C反应蛋白水平进行对照研究。结果：术前LH组和AH组免疫球蛋白及补体浓度相比无统计学差异(P＞0.05)。LH组手术前、后免疫球蛋白及补体均无显著变化(均P＞0.05)，AH组免疫球蛋白IgG、补体C3术后48h下降程度显著低于术前(P＜0.05)。术前LH组和AH组C反应蛋白浓度相比无统计学差异(P＞0.05)。虽然LH组和AH组术后48hC反应蛋白含量均明显高于术前(P＜0.05)，但是，AH组术后48h的血清C反应蛋白水平却显著高于LH组(P＜0.05)。经比较两组术后临床指标，LH组术中出血少、术后最高体温低、术后住院日短。结论：LH创伤较轻，引起机体免疫功能变化小，是真正意义上的微创手术。
Abstract:
Abstract Objective: To study the effect of laparoscopic hysterectomy (LH) and open hysterectomy (AH) on immune function. Methods: the serum immunoglobulin IgG, IgA, IgM, complement C3, C4 and creactive protein levels of 30 patients with laparoscopic hysterectomy (LH) and 30 patients with open hysterectomy (AH) were measured 24 hours before surgery and 48 hours after surgery. Results: there was no difference in immunoglobulin and complement concentrations between LH group and AH group before operation (P＞0.05). There were no significant changes in immunoglobulin and complement before and after operation in the LH group (all P were＞0.05), and the decreased degree of immunoglobulin IgG and complement C3 in the AH group was significantly lower than that before operation (P＜0.05). There was no difference in C reactive protein concentrations between the LH group and the AH group before surgery (P＞0.05). Although the content of creactive protein was significantly higher in both the LH group and the AH group 48 hours after surgery (P＜0.05), the level of serum creactive protein was significantly higher in the AH group 48 hours after surgery (P＜0.05). By comparing the postoperative clinical indicators of the two groups, the group of LH had less intraoperative bleeding, the maximum postoperative hypothermia, and the postoperative hospital stay was short. Conclusion: LH is a minimally invasive surgery because of its mild trauma and little changes in immune function.

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更新日期/Last Update: 2019-03-15