[1]王成均,侯 洪,曾幸萍,等.磁共振T2WI直方图在腰椎间盘退变中的应用价值研究*[J].陕西医学杂志,2019,(3):330-333,337.
　WANG Chengjun,HOU Hong,ZENG Xingping,et al.Value of T2WI histogram analysis in assessing lumbar intervertebral disc degeneration[J].,2019,(3):330-333,337.
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磁共振T2WI直方图在腰椎间盘退变中的应用价值研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年3期
页码:
330-333,337
栏目:
基础研究
出版日期:
2019-03-05

文章信息/Info

Title:
Value of T2WI histogram analysis in assessing lumbar intervertebral disc degeneration
文章编号:
DOI:10.3969/j.issn.10007377.2019.03.012
作者:
王成均1; 侯 洪2; 曾幸萍1; 陈 京1; 游述琴1; 欧阳祖彬
1.重庆市东南医院放射科（重庆401336）；2.重庆市东南医院急救部（重庆401336）；3.重庆医科大学附属第一医院放射科（重庆400016）
Author(s):
WANG Chengjun;  HOU Hong;  ZENG Xingping;  et al.
Department of Radiology, Chongqing Dongnan Hospital (Chongqing 401336)
关键词:
腰椎间盘退变; T2WI; 直方图; 磁共振成像; Pfirrmann分级
Keywords:
Key words Lumbar disc degeneration; T2WI; Histogram; Magnetic resonance imaging; Pfirrmann grade
分类号:
R445.4
文献标志码:
A
摘要:
摘 要 目的：探讨磁共振T2WI直方图在定量评价腰椎间盘退变中的价值。 方法：43例患者进行腰椎1.5T常规MRI T2WI检查，对椎间盘进行Pfirrmann分级，采用软件测量髓核T2WI信号强度(signal intensity, SI)直方图参数（平均值、标准差、偏度、峰度）。结果：椎间盘髓核T2WI SI平均值、标准差及偏度与Pfirrmann分级分别呈高度负相关(r=-0.83, P＜0.01)、中度负相关(r=-0.66, P＜0.01)及中度正相关(r=0.69, P＜0.01)。平均值、标准差在Ⅳ级与Ⅴ级间无统计学差异(P＞0.5)，在其余各级间均有统计学差异(P＜0.01)；偏度在所有各级间均存在统计学差异(P＜0.01)；峰度在Ⅰ～Ⅲ级间均无统计学差异，在其余各级间均存在统计学差异(P＜0.01)。Ⅰ～Ⅲ级椎间盘T2WI SI直方图为负偏态分布，高峰平缓；Ⅳ～Ⅴ级椎间盘为正偏态分布，高峰陡峭。对于鉴别Ⅰ级与Ⅱ级、Ⅱ级与Ⅲ级椎间盘，平均值、标准差及偏度ROC曲线均具有中等效能(P＜0.01)；对于鉴别Ⅲ级与Ⅳ级，平均值曲线效能最佳(P＜0.01)，峰度效能中等(P＜0.01)；对于鉴别Ⅳ级与Ⅴ椎间盘，偏度及峰度均具有中等效能(P均＜0.01)。结论： 磁共振T2WI信号直方图具有定量评价腰椎间盘退变的可行性，具有一定的临床参考价值。
Abstract:
Abstract Objective: To investigate the value of T2WI histogram analysis in assessing lumbar intervertebral disc degeneration on MRI. Methods: Fortythree patients were examined at 1.5 T MR by T2weighted sagittal imaging. For all patients, Pfirrmann grading system and T2WI histogram parameters(mean, standard deviation, skewness, kurtosis) were used to evaluate the degenerative degree of the discs. Results: The correlation between Pfirrmann grades with mean, standard deviation and skewness of T2WI signal intensity were significant negative, moderate negative and moderate positive, respectively(r=0.83,0.66,and 0.69,respectively, all P value ＜0.01). Except between grades IV and V, the differences of the mean and standard deviation between the rest of any 2 grades were significant(P＜0.01). No statistical difference of kurtosis were found between grade I to III, however, the rest of any 2 grades were significant(P＜0.01). There were significant differences in skewness between any 2 grades of all (P＜0.01). The histogram of the mean value of intervertebral disc with grade I to III was a negative skewness distribution with flat peak. In contrast, the histogram of grade IV and V was a positive skewness distribution with steep peak. For differentiating between grade I and II, II and III of intervertebral disc, the mean, standard deviation and skewness ROC curve have moderate efficiency(P＜0.01); For differentiating between grade III and IV, the mean value ROC curve showed the highest efficiency(P＜0.01); Both skewness and kurtosis can identify between grade IV and V, with its moderate efficiency(all P＜0.01). Conclusions: The T2WI histogram analysis has the feasibility of quantitative assessment of lumbar disc degeneration, which has some certain reference value for the clinic.

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备注/Memo

备注/Memo:
*重庆市卫生和计划生育委员会医学科研项目（2015MSXM011）
更新日期/Last Update: 2019-03-15