[1]朱喜明,谢念林,党海舟△.胸腔镜肺段切除术治疗老年早期非小细胞肺癌近期疗效及对患者肺功能的影响研究*[J].陕西医学杂志,2019,(12):1638-1641.
　ZHU Ximing,XIE Nianlin,DANG Haizhou.Shortterm efficacy of thoracoscopic segmentectomy on elderly early nonsmall cell lung cancer and its effects on lung function[J].,2019,(12):1638-1641.
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胸腔镜肺段切除术治疗老年早期非小细胞肺癌近期疗效及对患者肺功能的影响研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年12期
页码:
1638-1641
栏目:
临床研究
出版日期:
2019-12-05

文章信息/Info

Title:
Shortterm efficacy of thoracoscopic segmentectomy on elderly early nonsmall cell lung cancer and its effects on lung function
文章编号:
DOI:10.3969/j.issn.10007377.2019.12.016
作者:
朱喜明; 谢念林; 党海舟△
空军军医大学唐都医院胸外科（西安 710038）
Author(s):
ZHU Ximing; XIE Nianlin; DANG Haizhou
Thoracic Surgery Tangdu Hospital of PLA Air Force Military Medical University (Xi’an 710038)
关键词:
胸腔镜肺段切除术; 胸腔镜肺叶切除术; 老年人; 早期非小细胞肺癌; 肺功能; 疗效
Keywords:
Key words Thoracoscopic segmentectomy; Thoracoscopic lobectomy; Elderly; Early nonsmall cell lung cancer; Pulmonary function; Efficacy
分类号:
R7342
文献标志码:
A
摘要:
摘 要 目的：研究胸腔镜肺段切除术治疗老年早期非小细胞肺癌（NSCLC）的近期疗效及对患者肺功能的影响。 方法：收集老年NSCLC患者69例，根据患者手术方式将其分为段切组（胸腔镜肺段切除术，n=33）与叶切组（胸腔镜下肺叶切除术，n=36），观察两组手术效果。 结果：段切组中，13例患者肿瘤位于左肺，10例患者肿瘤位于右肺；叶切组中，16例患者肿瘤位于左肺，20例患者肿瘤位于右肺。病理检查提示，两组病理类型比较有统计学差异（P＜005），其中全切组患者以微浸润性腺癌为主，叶切组以浸润性腺癌为主，两组病理分期比较无统计学差异（P＞005）；两组淋巴结清扫个数、纵膈淋巴结清扫站数及纵膈淋巴结清扫个数比较均无统计学差异（P＞005）； 两组手术时间比较无统计学差异（P＞005），段切组患者术中出血量、术后总引流量、胸腔引流量、术后应用抗生素时间、ICU停留时间及术后住院时间均显著少于/短于叶切组（P＜005）； 两组术后并发症比较无统计学差异（P＞005）；Log Rank检验提示，两组3年生存情况比较无统计学差异（P＞005）。 结论：胸腔镜肺段切除术能保留更多的肺组织，术后残腔小，能减少术后引流量，降低术后并发症率，利于老年NSCLC患者术后早期恢复，且远期疗效与胸腔镜肺叶切除术相似。
Abstract:
Abstract Objective：To study the shortterm efficacy of thoracoscopic segmentectomy on elderly early nonsmall cell lung cancer (NSCLC) and its effects on lung functionMethods:Regression analysis was performed on clinical data of elderly NSCLC patients 69 cases,and the patients were divided into segmentectomy group (thoracoscopic segmentectomy,n=33) and lobectomy group (thoracoscopic lobectomy,n=36) according to the surgical methods of patientsThe surgical effects were observed in the two groupsResults:In segmentectomy group,the tumors of 13 patients were located in the left lung and the tumors of 10 patients were located in the right lung,and in lobectomy group,the tumors of 16 patients were located in the left lung and the tumors of 20 patients were located in the right lungPathological examination suggested that there were significant differences in the pathological types between the two groups (P＜005)Segmentectomy group was mainly microinvasive adenocarcinoma,and lobectomy group was mainly invasive adenocarcinoma,and there was no significant difference in pathological stage between the two groups (P＞005)There were no significant differences in the number of lymph node dissection,number of mediastinal lymph node dissection station and number of mediastinal lymph node dissection (P＞005)There was no significant difference in the operative time between the two groups (P＞005),and the intraoperative blood loss,total postoperative drainage,chest drainage,postoperative antibiotic time,ICU stay time and postoperative hospital stay in segmentectomy group were significantly less/shorter than those in lobectomy group (P＜005)There were no significant differences in postoperative complications between the two groups (P＞005)Log Rank test showed that there was no significant difference in the 3year survival curve between the two groups (P＞005)Conclusion:Thoracoscopic segmentectomy can preserve more lung tissuse with small postoperative residual cavity,and can reduce postoperative 〖LM〗drainage and lower postoperative incidence rate of complicationsIt is beneficial for early postoperative recovery of elderly patients with NSCLC,and its longterm efficacy is similar to thoracoscopic lobectomy

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备注/Memo

备注/Memo:
*陕西省卫生和计划生育委员会科研项目（2016D10467）
更新日期/Last Update: 2019-12-19