[1]郭 强,康 超△,高晓猛,等.双极调压脉冲射频联合小剂量胶原酶治疗腰椎间盘突出症29例临床研究*[J].陕西医学杂志,2019,(12):1627-1629，1633.
　GUO Qiang,KANG Chao,GAO Xiaomeng,et al.The clinical effects of the bipolar needle manual pressure regulator pulsed radiofrequency combined small dose of collagenase on lumbar intervertebral disc herniation[J].,2019,(12):1627-1629，1633.
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双极调压脉冲射频联合小剂量胶原酶治疗腰椎间盘突出症29例临床研究*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年12期
页码:
1627-1629，1633
栏目:
临床研究
出版日期:
2019-12-05

文章信息/Info

Title:
The clinical effects of the bipolar needle manual pressure regulator pulsed radiofrequency combined small dose of collagenase on lumbar intervertebral disc herniation
文章编号:
DOI:10.3969/j.issn.10007377.2019.12.013
作者:
郭 强1;  康 超2△;  高晓猛1;  党彩艳1
1西安交通大学附属西安市中心医院疼痛科（西安710004）；2 西北妇女儿童医院麻醉科（西安710061）
Author(s):
GUO Qiang; KANG Chao; GAO Xiaomeng; et al
Department of Pain，Xi’an Central Hospital (Xi’an 710004）
关键词:
腰椎间盘突出症; 双极调压脉冲射频; 小剂量胶原酶; 溶解术; 胶原酶溶盘术
Keywords:
Key words Lumbar intervertebral disc herniation; Bipolar needle manual pulsed radiofrequency; Small dose of collagenase; Dissolution; Collagen disk
分类号:
R6815
文献标志码:
A
摘要:
摘 要 目的：探讨双极调压脉冲射频联合小剂量胶原酶治疗腰椎间盘突出症的临床疗效及安全性。方法：选择腰椎间盘突出症患者60例，随机分为双极调压脉冲射频联合小剂量胶原酶溶解术治疗组（A组29例）和胶原酶盘外溶盘术治疗组（B组31例）；分别在C臂机引导下完成手术。采用改良Macnab方法评估观察术后1周、1月、3月、6月的疗效，并记录术后不良反应；测量并对比术前与术后3月、6月椎间盘突出指数及CT值。结果：A组患者术后1周、1月、3月和6月优良率明显高于B组，组间相比差异有统计学差异（P＜005）；两组患者术后3月、6月的椎间盘突出指数较治疗前相比差异有统计学差异（P＜005），组间比较无统计学差异。结论：双极调压脉冲射频联合小剂量胶原酶治疗腰椎间盘突出症较单纯胶原酶盘外溶盘术治疗疗效更好、更安全，能有效避免较大剂量的胶原酶引起的潜在并发症。
Abstract:
Abstract Objective：To explore the clinical effects and safety of the bipolar needle manual pressure regulator pulsed radiofrequency combined small dose of collagenase on lumbar intervertebral discherniation(LIDH)．Methods：60 patients with LIDH were treated with bipolar needle manual pressure regulator pulsed radiofrequency．The patients were followed up at 1 week，1 month，3 month and 6 month after treatment．The clinical effects were evaluated with modified Macnab method and side effects were recorded.The index and CT value of intervertebral disc were measured and compared before and after operation Results：The excellent and good rates of group A was significantly higher than group B in 1 week，1 month，3 months and 6 months after surgery.In the two groups，the index of intervertebral disc herniation in 3 months and 6 months after surgery was significantly different than before treatment.There was no significant differences between groups．Conclusion：Bipolar needle manual pressure regulator pulsed radiofrequency is more safe and effective minimally invasive treatment for LIDH

参考文献/References:

[1] 韩春鸣，常德海，康万年，等运用后路椎间盘镜下髓核摘除治疗腰椎间盘突出症的临床研究[J] .陕西医学杂志，2015，44（8）：963965
[2] 吕正茂，杨利学，谭龙旺，等CT引导下射频热凝配合功能锻炼治疗腰椎间盘突出症118例[J] .陕西医学杂志，2011，40（4）：507508
[3] Mac Nab INegative disc exploration:an analysis of the causes of nerve root involvement in sixty eight patients[J] .J Bone Joint Surg(Am),1971,53(8):891903
[4] 王志剑，张学学，翁泽林，等靶点射频联合盘内小剂量胶原酶注射治疗腰椎间盘突出症的临床观察[J] . 中国疼痛医学杂志，2011，17(7)：390392．
[5] Birkenmaier C,Komp M,Leu HF,et al.The current state of endoscopic disc surgery:Review of controlled studies comparing fullendoscopic procedures for disc herniations to standard procedures[J] .Pain Physician,2013,16:335344
[6] 王军峰，王 亮，卫健民腰椎间孔镜手术治疗腰椎间盘突出症临床研究[J] .陕西医学杂志，2018，47（4）：454456
[7] 赵 伟，李长青，周 跃，等经皮椎间孔镜下TESSYS技术治疗腰椎间盘突出症[J] .中国矫形外科杂志，2012,20（13）：11911195
[8] 许成君射频联合胶原酶盘内治疗腰椎间盘突出症的对照研究[J] .颈腰痛杂志，2013,34（6）：493496
[9] 王晓明，念其进，陈 斌，等．胶原酶溶解术与胶原酶加臭氧联合注射治疗腰椎间盘突出症的疗效观察[J] .中国骨与关节杂志， 2015，30(9)：972974．
[10] 银和平，李树文，杜志才，等经皮穿刺切吸与臭氧射频组合应用治疗腰椎间盘突出症[J] .中国骨与关节杂志， 2014，28(7)：609610．
[11] 张达颖． 胶原酶化学溶解术治疗腰椎间盘突出症不良事件的防治[J] ．中国疼痛医学杂志，2007，13：380382．
[12] 何鹏宇，林志义，牟明威低温等离子髓核消融术配合穴位埋线治疗腰椎间盘突出症疗效观察[J] .陕西中医，2015，36（4）：438441
[13] 程 涛，全 健射频热凝加臭氧治疗腰椎间盘突出症60例临床观察[J] .陕西医学杂志，2016，45（10）：13421343
[14] Van Boxem K,van Bilsen J,de Meij N,et al.Pulsed radiofrequency treatment adiacent to the lumbar dorsal root ganglion for the management of lumbosacral radicular syndrome:a clinical audit[J] .Pain Med,2011,12:13221330
[15] 王迎虎，杜洪印，谭建强，等 突出物 CT 值对胶原酶治疗颈椎间盘突出症疗效的相关性研究[J] . 中国疼痛医学杂志，2014，20(12):909914

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备注/Memo

备注/Memo:
*西安市卫生科技项目（J201701008）
更新日期/Last Update: 2019-12-19