[1]李 卉.成比例辅助机械通气在急性呼吸衰竭患者中应用效果评价*[J].陕西医学杂志,2019,(1):28-31.
　LI Hui..Therapeutic effects of proportional assist ventilation on patients with acute respiratory failure[J].,2019,(1):28-31.
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成比例辅助机械通气在急性呼吸衰竭患者中应用效果评价*
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《陕西医学杂志》[ISSN:1000-7377/CN:61-1281/TN]

卷:
期数:
2019年1期
页码:
28-31
栏目:
临床研究
出版日期:
2019-01-05

文章信息/Info

Title:
Therapeutic effects of proportional assist ventilation on patients with acute respiratory failure
文章编号:
DOI:10.3969/j.issn.10007377.2019.01.009
作者:
李 卉
成都大学附属医院重症监护室（成都 610000）
Author(s):
LI Hui.
Department of Intensive Care Unit,the Affiliated Hospital of Chengdu University（Chengdu 610000）
关键词:
成比例辅助通气; 急性呼吸衰竭; 舒适度; 气道峰压; 口腔漏气评分; 人机协调
Keywords:
Key words Proportional assisted ventilation; Acute respiratory failure; Comfort; Airway peak; Oral leak rating; Manmachine coordination
分类号:
R563.8
文献标志码:
A
摘要:
摘 要 目的：探讨无创成比例辅助机械通气(PAV)与BiPAP(S/T) 相比对急性呼吸衰竭患者临床效果和舒适度的影响。方法：研究纳入急性呼吸衰竭患者30例，在常规药物治疗的基础上，应用无创BiPAP(S/T)模式与成比例辅助机械通气(PAV)模式进行辅助治疗，观察并比较不同模式下患者的动脉血气分析指标\[包括血氧分压( PaO2) 、血二氧化碳分压( PaCO2) 、血氧饱和度( SaO2) 、pH值（BE）\]、呼吸力学指标\[吸入氧浓度(FiO2 )、潮气量(VT)、气道峰压(PIP)、吸气/呼吸周期时间比(Ti/Ttotal)、每分钟通气量(MV)、呼吸频率(RR)、平均吸气流速(VT/Ti)）和舒适度\]。结果：经过PAV模式通气治疗后患者PaO2、PaCO2、SaO2、pH值、BE、FiO2、VT、Ti/Ttotal、MV、RR、VT/Ti与BiBAP模式通气治疗后比较，两种模式指标差异无统计学意义（P＞0.05）；经过PAV模式通气治疗后患者通气时的PIP显著降低(P＜0.05)；比较两种通气方面患者舒适度，患者鼻面罩舒适度、呼吸困难评分比较差异无统计学意义( P＞0.05) ，PAV模式通气治疗后患者口鼻咽干燥、口腔漏气评分明显低于BiPAP模式通气治疗后( P＜0.05)。结论：与BiPAP模式相比， PAV模式应用于患者时气道峰压低、通气依从性好，具有更好的人机协调性。
Abstract:
Abstract Objective：To investigate the effect of noninvasive proportional assisted mechanical ventilation (PAV) compared with BiPAP (S/T) on the clinical efficacy and comfort of patients with acute respiratory failure. Methods：In the study,30 patients with acute respiratory failure were included. Based on conventional drug therapy,noninvasive BiPAP (S/T) mode and proportional assisted mechanical ventilation (PAV) mode were used for adjuvant therapy to observe and compare arterial blood gas in patients with different modes. Analytical indicators (including PaO2,PaCO2,SaO2,pH),respiratory mechanics (inhaled oxygen concentration (FiO2),tidal volume (VT) Peak Air Pressure (PIP),Inspiratory/Respiratory Cycle Time Ratio (Ti/Ttotal),Minute Ventilation (MV),Respiratory Frequency (RR),Average Inspiratory Flow Velocity (VT/Ti) and Comfort. Results: There was no significant difference between the two groups after PaO2,PaCO2,SaO2,pH,BE,FiO2,VT,Ti/Ttotal,MV,RR,VT/Ti,and BiBAP mode ventilation after PAV mode ventilation treatment. 0.05); after PAV mode ventilation treatment,patients' PIP was significantly decreased after ventilation (P＜0.05); comparing patients' comfort of the two types of ventilation,there was no significant difference in patients' nasal mask comfort and dyspnea scores (P＞0.05),Oral and nasopharynx dryness and oral air leakage scores after PAV ventilation therapy were significantly lower than those after BiPAP ventilation (P＜0.05). Conclusion:Compared with the BiPAP model,the PAV model was applied to patients with low peak airway pressure,good ventilation compliance,and better manmachine coordination.

参考文献/References:

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备注/Memo

备注/Memo:
*四川省卫生和计划生育委员会科研课题（17PJ141）
更新日期/Last Update: 2019-01-22